USP9X Monoclonal Antibody (OTI2B4), TrueMAB™, OriGene

Mouse Monoclonal Antibody

Supplier:  OriGene TA800061

Catalog No. 50-167-8048

Description

USP9X is an ubiquitin-specific protease involved in the removal and recycling of ubiquitin from proteins degraded in proteasomes. As a deubiquitinating enzyme, USP9x has a critical function in tight junction biogenesis by controlling the levels of the exchange factor for Arf6 (EFA6), a protein shown to facilitate tight junction formation during a narrow temporal window preceding the establishment of cell polarity (1). USP9X is also located on the X-chromosome but escapes X-inactivation, and defects in USP9X may cause gonadal degeneration in Turner syndrome.

Specifications

• Antigen: USP9X
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
• Gene Accession No.: Q93008
• Gene Symbols: USP9X
• Immunogen: Human recombit protein fragment corresponding to amino acids 2246-2570 of human USP9X produced in E.coli.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: Western Blot
• Clone: OTI2B4
• Conjugate: Unconjugated
• Gene: USP9X
• Gene Alias: DFFRX, FAF, FAM, MRX99, MRXS99F
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 8239
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Liquid