USP9X Mouse anti-Canine, Human, Mouse, Rat, Clone: OTI2G7, lyophilized, TrueMAB™

Mouse Monoclonal Antibody

Supplier:  OriGene CF800088

Catalog No. 50-166-4849

Description

Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO

USP9X is an ubiquitin-specific protease involved in the removal and recycling of ubiquitin from proteins degraded in proteasomes. As a deubiquitinating enzyme, USP9x has a critical function in tight junction biogenesis by controlling the levels of the exchange factor for Arf6 (EFA6), a protein shown to facilitate tight junction formation during a narrow temporal window preceding the establishment of cell polarity (1). USP9X is also located on the X-chromosome but escapes X-inactivation, and defects in USP9X may cause gonadal degeneration in Turner syndrome.

Specifications

• Antigen: USP9X
• Classification: Monoclonal
• Conjugate: Unconjugated
• Gene: USP9X
• Gene Alias: DFFRX, FAF, FAM, MRX99, MRXS99F
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 22284, 363445, 480885, 8239
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Lyophilized

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Clone: OTI2G7
• Formulation: PBS with 8% trehalose and no preservative; pH 7.3
• Gene Accession No.: P70398, Q93008
• Gene Symbols: Usp9x
• Immunogen: Human recombit protein fragment corresponding to amino acids 2246-2570 of human USP9X produced in E.coli.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Canine, Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG2a