Invitrogen™ USP9X Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA523035

Catalog No. PIPA523035

Description

The target sequence has 95% sequence homology with rat and 80% sequence homology with zebrafish.

USP9X is an ubiquitin-specific protease involved in the removal and recycling of ubiquitin from proteins degraded in proteasomes. As a deubiquitinating enzyme, USP9x has a critical function in tight junction biogenesis by controlling the levels of the exchange factor for Arf6 (EFA6), a protein shown to facilitate tight junction formation during a narrow temporal window preceding the establishment of cell polarity. USP9X is also located on the X-chromosome but escapes X-inactivation, and defects in USP9X may cause gonadal degeneration in Turner syndrome.

Specifications

• Antigen: USP9X
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: USP9X
• Gene Alias: 5730589N07Rik; AA407302; AA407699; AL022658; AL022749; Deubiquitinating enzyme FAF-X; DFFRX; Drosophila fat facets related, X-linked; FAF; Fafl; FAF-X; FAM; fat facets homolog; Fat facets in mammals; fat facets protein related, X-linked; fat facets protein-related, X-linked; fats facets protein related, X; hFAM; MRX99; MRXS99F; Probable ubiquitin carboxyl-terminal hydrolase FAF-X; putative ubiquitin carboxyl-terminal hydrolase FAF-X; putative ubiquitin carboxyl-terminal hydrolase FAF-x-like protein; RGD1560056; Ubiquitin carboxyl-terminal hydrolase FAM; ubiquitin specific peptidase 9 X-linked; ubiquitin specific peptidase 9, X chromosome; ubiquitin specific peptidase 9, X-linked; ubiquitin specific protease 9 SSSRF- isoform; ubiquitin specific protease 9, X chromosome; ubiquitin specific protease 9, X chromosome (fat facets-like Drosophila); ubiquitin specific protease 9, X-linked; ubiquitin thioesterase FAF-X; ubiquitin thiolesterase FAF-X; ubiquitin-specific processing protease FAF-X; ubiquitin-specific protease 9, X chromosome; Ubiquitin-specific-processing protease FAF-X; USP9; USP9X
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 22284, 363445, 8239
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 0.2 mg/mL
• Formulation: PBS with 0.1% BSA, 30% glycerol and 0.05% sodium azide
• Gene Accession No.: P70398, Q93008
• Gene Symbols: USP9X
• Immunogen: Genomic peptide made to an internal region of the human Usp9X protein (within residues 1150-1300).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG