Invitrogen™ UT-A1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA577786

Catalog No. PIPA577786

Description

1 μg/mL of PA5-77786 was sufficient for detection of UT-A1 in 20 μg of rat kidney tissue lysate by colorimetric immunoblot analysis using Goat anti-rabbit IgG:HRP as the secondary antibody. Detects approximately 97 and 127kDa.

UT-A1, a kidney-specific urea transporter is expressed in the renal collecting duct where it mediates trans-epithelial urea transport and is a target for regulation by vasopressin. Urea movement out of the collecting duct in the inner medulla of the kidney allows accumulation of urea in the medullary interstitium, thereby allowing maximum water reabsorption from the collecting ducts.

Specifications

• Antigen: UT-A1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Slc14a2
• Gene Alias: FLJ16167; HUT2; hUT-A6; MGC119566; MGC119567; plasma membrane urea transporter; SLC14A2; Slc14a2_v4; Slc14a2T; solute carrier family 14 (urea transporter), member 2; solute carrier family 14 (urea transporter), member 2, variant 4; solute carrier family 14 (urea transporter), member 2T; solute carrier family 14 member 2; solute carrier family 14, member 2; testName; testSymbol; urea transport protein; urea transporter 2; Urea transporter, kidney; urea transporter-2; UrT1-C; UrT1-D; UT1; UT2; UTA; UTA1; UT-A1; UT-A2; UT-A3; UTR
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography, Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 27411, 54302
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.09% sodium azide; pH 7.4
• Gene Accession No.: Q62668, Q8R4T9
• Gene Symbols: Slc14a2
• Immunogen: Produced against a synthetic peptide mapped to the C-terminal tail (amino acids 911-929) of rat UT-A1 (antibody designation L194).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Mouse, Rat
• Product Type: Antibody
• Isotype: IgG