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Invitrogen™ Uteroglobin Polyclonal Antibody
Rabbit Polyclonal Antibody
Supplier: Invitrogen™ PA595864
Description
Immunogen sequence: EICPSFQRVI ETLLMDTPSS YEAAMELFSP DQDMREAGAQ LKKLVDTLPQ KPRESIIKLM EKIAQSSLCN.
Uteroglobin, which is a member of the Secretoglobin superfamily and is also known as Clara cell phospholipid-binding protein, is a multifunctional protein that can exert anti-inflammatory and anti-tumorigenic effects by binding small hydrophobic molecules such as phospholipids and prostaglandins. The small, non-glycosylated protein named for its high levels of expression in pre-implantation embryos, where it exhibits growth stimulatory effects, is produced and secreted by the non-ciliated, non-mucous Clara cells predominant in the epithelial surfaces of pulmonary airways, as well as other non-ciliated epithelia. Members of the Secretoglobin superfamily demonstrate a high level of structural conservation and are characterized as small, secretory homo- or heterodimers. In addition to sequestering pro-inflammatory mediators and carcinogens, Uteroglobin has been implicated in the inhibition of cell migration and invasion, platelet aggregation, and T cell differentiation.
Specifications
Uteroglobin | |
Polyclonal | |
Unconjugated | |
SCGB1A1 | |
Blastokinin; CC10; CC16; CCPBP; CCSP; Clara cell 17 kDa protein; clara cell phospholipid-binding protein; clara cell secretory protein; clara cells 10 kDa secretory protein; PCBB; PCB-binding protein; PCB-BP; SCGB1A1; Secretoglobin family 1A member 1; secretoglobin, family 1A, member 1 (uteroglobin); UG; Ugb; UP1; UP-1; Urinary protein 1; urine protein 1; uteroglobin; Uteroglobin (Clara cell secretory protein); Utg | |
Rabbit | |
Affinity Chromatography | |
RUO | |
22287, 25575 | |
-20°C, Avoid Freeze/Thaw Cycles | |
Liquid |
ELISA, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry | |
1.32 mg/mL | |
PBS with 50% glycerol and 0.09% sodium azide; pH 7.3 | |
P17559, Q06318 | |
SCGB1A1 | |
Recombinant fusion protein containing a sequence corresponding to amino acids 22-91 of human SCGB1A1 (NP_0033481). | |
100 μL | |
Primary | |
Mouse, Rat | |
Antibody | |
IgG |
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