Invitrogen™ Uteroglobin Recombinant Rabbit Monoclonal Antibody (122)

Catalog No.	Quantity
PIMA529780	100 μL

Catalog No. PIMA529780 Supplier Invitrogen™ Supplier No. MA529780

Description

Rabbit Recombinant Monoclonal Antibody

This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%). Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire. This antibody has specificity for Mouse Uteroglobin/SCGB1A1.

Uteroglobin, which is a member of the Secretoglobin superfamily and is also known as Clara cell phospholipid-binding protein, is a multifunctional protein that can exert anti-inflammatory and anti-tumorigenic effects by binding small hydrophobic molecules such as phospholipids and prostaglandins. The small, non-glycosylated protein named for its high levels of expression in pre-implantation embryos, where it exhibits growth stimulatory effects, is produced and secreted by the non-ciliated, non-mucous Clara cells predominant in the epithelial surfaces of pulmonary airways, as well as other non-ciliated epithelia. Members of the Secretoglobin superfamily demonstrate a high level of structural conservation and are characterized as small, secretory homo- or heterodimers. In addition to sequestering pro-inflammatory mediators and carcinogens, Uteroglobin has been implicated in the inhibition of cell migration and invasion, platelet aggregation, and T cell differentiation.

Specifications

• Antigen: Uteroglobin
• Applications: Immunohistochemistry (Paraffin)
• Classification: Recombinant Monoclonal
• Clone: 122
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with no preservative
• Gene: SCGB1A1
• Gene Accession No.: Q06318
• Gene Alias: Blastokinin; CC10; CC16; CCPBP; CCSP; Clara cell 17 kDa protein; clara cell phospholipid-binding protein; clara cell secretory protein; clara cells 10 kDa secretory protein; PCBB; PCB-binding protein; PCB-BP; SCGB1A1; Secretoglobin family 1A member 1; secretoglobin, family 1A, member 1 (uteroglobin); UG; Ugb; UP1; UP-1; Urinary protein 1; urine protein 1; uteroglobin; Uteroglobin (Clara cell secretory protein); Utg
• Gene Symbols: SCGB1A1
• Host Species: Rabbit
• Immunogen: Recombinant Mouse Uteroglobin/SCGB1A1 protein.
• Purification Method: Protein A
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 22287
• Target Species: Mouse
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG