Vγ 2 T-Cell Receptor Hamster anti-Mouse, BUV395, Clone: UC3-10A6, BD Optibuild™
Armenian Hamster Monoclonal Antibody
Manufacturer: BD Biosciences 742314
The UC3-10A6 monoclonal antibody specifically recognizes T-cell Receptor (TCR) V gamma 2 (Vγ2).Vγ2+ TCRγδcells make up significant proportions of TCRγδcells in the late fetal and adult thymus and adult peripheral lymphoid tissues and lung. The frequency of splenicVγ2+ TCRγδcells differs among inbred mouse strains; in C57BL/6 mice, the frequency increases dramatically during the four weeks after birth. Immobilized UC3-10A6 antibody can activateVγ2+TCRγδ cells. Please note that the Vγ2 designation correlates with the nomenclature of Garman, Doherty, and Raulet; the Vγ4 designation of Heiligand Tonegawa is equilvalent.The antibody was conjugated to BD Horizon™ BUV395 which is part of the BD Horizon Brilliant™ Ultraviolet family of dyes. This dye has been exclusively developed by BD Biosciences to have minimal spillover into other detectors, making it an optimal choice for multicolor flow cytometry. With an Ex Max at 348 nm and an Em Max at 395 nm, BD Horizon BUV395 can be excited with a 355 nm laser and detected with a 379/28 filter. BUV395 is a UV-excitable dye that has been developed exclusively by BD Biosciences. With an excitation max of 348 nm and emission max of 395 nm, BUV395 can be excited by the 355nm laser and detected in a 379/28 filter. This dye is optimal for multicolor flow cytometry because it has little to no spillover into other detectors.
|Vγ 2 T-Cell Receptor|
|Aqueous buffered solution containing ≤0.09% sodium azide.|
|V gamma 2 TCR, Vγ2 TCR, Trgv2|
|The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography. The antibody was conjugated with BD Horizon BUV395 under optimal conditions that minimize unconjugated dye and antibody.|
|Brilliant Ultraviolet 395|
|Armenian Hamster IgG1, κ|
|Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.|
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