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Vγ9 TCR Mouse anti-Human, Brilliant Violet 421, Clone: B3, BD Optibuild™

Catalog No. BDB744034 Shop All BD Biosciences Products
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BDB744034 50 μg
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Catalog No. BDB744034 Supplier BD Biosciences Supplier No. 744034
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Description

Mouse Monoclonal Antibody

The B3 monoclonal antibody specifically recognizes the human variableγ9 subunit (Vγ9) ofγ/δ T- cell receptor (TCR). Theγ/δTCR is composed of two disulfide-linked glycoproteins. The gamma chain is approximately 45-60 kD and is detected on a small subset peripheral blood T cells and thymocytes. The majority of normal peripheral bloodγ/δT cells express a Vγ9+/Vδ2+ phenotype. The reason for this selection in the T-cell repertoire is not well understood.

The antibody was conjugated to BD Horizon™ BV421 which is part of the BD Horizon Brilliant™ Violet family of dyes. With an Ex Max of 407nm and Em Max at 421nm, BD Horizon BV421 can be excited by the violet laser and detected in the standard Pacific Blue™ filter set (eg, 450/50nm filter). BD Horizon BV421 conjugates are very bright, often exhibiting a 10 fold improvement in brightness compared to Pacific Blue conjugates. BV421 is a polymer-based dye excited by the violet laser and is one of the brightest fluorochromes offered by BD Biosciences. Conjugates are typically 10 times brighter than Pacific Blue™ conjugates and are often as bright as or brighter than PE conjugates. Due to nearly identical excitation and emission properties but different spillover characteristics, BD Horizon BV421, Pacific Blue™, and BD Horizon™ V450 cannot be used simultaneously.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Vγ9 TCR
Classification Monoclonal
Clone B3
Concentration 0.2mg/mL
Conjugate Brilliant Violet 421
Formulation Aqueous buffered solution containing ≤0.09% sodium azide.
Gene Alias Vgamma9 TCR, V2, TRGC1, TCRGV9, TRGV9
Host Species Mouse
Purification Method Affinity Purified
Quantity 50 μg
Regulatory Status RUO
Primary or Secondary Primary
Target Species Human
Content And Storage Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Isotype IgG1 κ
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Safety and Handling

WARNING: Reproductive Harm - www.P65Warnings.ca.gov
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