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V Bta 9 TCR Mouse, anti-Mouse, R718, Clone: MR10-2, BD OptiBuild™

Mouse Monoclonal Antibody

Manufacturer:  BD Biosciences 751987

Catalog No. BDB751987


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Description

Description

The MR10-2 monoclonal antibody reacts with the Vβ9 T-cell Receptor (TCR) of mice having the b haplotype (e.g., A, BALB/c, CBA/Ca, C3H/He, C57BL) of the Tcrb gene complex. The Tcrb-V9 gene locus is deleted in mice having the a (e.g., C57BR, C57L, SJL, SWR) or c (e.g., RIII) haplotype. Vβ9-bearing T lymphocytes are clonally eliminated in mice expressing superantigen encoded by Mtv-7 (Mls-1a, Mlsa) provirus (e.g., AKR, CBA/J, DBA/2), and activation or elimination of Vβ9 TCR-expressing T cells by this determinant is partially dependent upon presentation by I-E. Mtv-43 (e.g., MA/MyJ), Mtv-44 (e.g., NZW), and/or exogenous MMTV-SW superantigens also cause incomplete elimination of Vβ9 TCR-bearing T cells. Plate-bound MR10-2 antibody activates Vβ9 TCR-bearing T cells.

Specifications

Specifications

V Bta 9 TCR
MR10-2
Liquid
50 μg
Refrigerate Upon Arrival
Monoclonal
Flow Cytometry
R718
Mouse
RUO
Primary
Mouse
SDS
Documents
Product Certifications
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