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Invitrogen™ v-Myb Polyclonal Antibody
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Catalog No. PIPA552611
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100 μL
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PIPA552611 100 μL
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Catalog No. PIPA552611 Supplier Invitrogen™ Supplier No. PA552611
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: EANAVLSSLQ TIPEFAETLE LIESDPVAWS DVTSFDISDA AASPIKSTPV KLMRIQHNEG AMECQFNVSL VLEGKKNTCN GGNSEAVPLT SPNIAKFSTP PAILRKKRKM RVGHSPGSEL RDGSLNDGGN Highest antigen sequence identity to the following orthologs: Mouse - 86%, Rat - 85%.

A-Myb is expressed at specific times in reproductive tissues, some neural cells, and a subset of normal and neoplastic B lymphocytes. Both A-Myb and B-Myb are expressed in t(14:18) lymphoma cells where they then inhibit cell arrest and apoptotic signaling. Expression of B-Myb rescues cells from p53-induced G1 phase arrest that is mediated by p21, while A-Myb functions as an anti-apoptotic factor by effectively activating the bcl-2 promoter and thereby up-regulating Bcl-2 expression.
TRUSTED_SUSTAINABILITY

Specifications

Antigen v-Myb
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 0.1 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene MYBL1
Gene Accession No. P10243
Gene Alias AMYB; A-myb; G1-419-6; MYB proto-oncogene like 1; MYBA; MYBL1; myb-like protein 1; Myb-related protein A; myeloblastosis oncogene-like 1; repro9; VMYB; v-myb avian myeloblastosis viral oncogene homolog-like 1
Gene Symbols MYBL1
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human v-Myb. Recombinant protein control fragment (Product #RP-89420).
Purification Method Antigen Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 4603
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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