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Invitrogen™ v-Myb Polyclonal Antibody
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Catalog No. PIPA575222
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100 μL
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Catalog No. Quantity
PIPA575222 100 μL
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Catalog No. PIPA575222 Supplier Invitrogen™ Supplier No. PA575222
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Description

Rabbit Polyclonal Antibody

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

A-Myb is expressed at specific times in reproductive tissues, some neural cells, and a subset of normal and neoplastic B lymphocytes. Both A-Myb and B-Myb are expressed in t(14:18) lymphoma cells where they then inhibit cell arrest and apoptotic signaling. Expression of B-Myb rescues cells from p53-induced G1 phase arrest that is mediated by p21, while A-Myb functions as an anti-apoptotic factor by effectively activating the bcl-2 promoter and thereby up-regulating Bcl-2 expression.
TRUSTED_SUSTAINABILITY

Specifications

Antigen v-Myb
Applications Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 15mM sodium azide; pH 7.2
Gene MYBL1
Gene Accession No. P10243, P51960
Gene Alias AMYB; A-myb; G1-419-6; MYB proto-oncogene like 1; MYBA; MYBL1; myb-like protein 1; Myb-related protein A; myeloblastosis oncogene-like 1; repro9; VMYB; v-myb avian myeloblastosis viral oncogene homolog-like 1
Gene Symbols MYBL1
Host Species Rabbit
Immunogen Synthetic peptide corresponding to amino acids 221-270 of Human v-Myb.
Purification Method Antigen Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 17864, 297783, 4603
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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