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  6. Invitrogen™ Valproic Acid Monoclonal Antibody (VP10-115.2), Invitrogen™

Invitrogen™ Valproic Acid Monoclonal Antibody (VP10-115.2), Invitrogen™
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Catalog No. 01671995
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500 μg
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Catalog No. Quantity
01-671-995 500 μg
PIMA546132 100 μg
PIMA546135 1 mg
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Catalog No. 01-671-995 Supplier Invitrogen™ Supplier No. MA110765
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Description

Mouse Monoclonal Antibody

MA1-10765 detects Valproic Acid. MA1-10765 has been successfully used in ELISA applications. The MA1-10765 immunogen is Valproic acid, conjugated to KLH.

Valproic acid, valproate sodium, and divalproex belong to the group of medicines called anticonvulsants. They are used to control certain types of seizures in the treatment of epilepsy. Also Valproic acid relieves histone deacetylases (HDACs) dependent transcriptional repression and causes hyperacetylation of histones in cultured cells and in vivo. Valproic acid inhibits HDAC activity in vitro, most probably by binding to the catalytic center of HDACs. Most importantly, valproic acid induces differentiation of carcinoma cells, transformed hematopoietic progenitor cells and leukemic blasts from acute myeloid leukemia patients. More over, tumor growth and metastasis formation are significantly reduced in animal experiments. Therefore, valproic acid might serve as an effective drug for cancer therapy.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Valproic Acid
Applications ELISA
Classification Monoclonal
Clone VP10-115.2
Concentration 1.3 mg/mL
Conjugate Unconjugated
Formulation PBS with no preservative; pH 7.4
Gene Alias C8H16O2; Depakene; Depakine; Dipropylacetic acid
Host Species Mouse
Immunogen Valproic acid, conjugated to KLH.
Purification Method Protein G
Quantity 500 μg
Regulatory Status RUO
Primary or Secondary Primary
Target Species Chemical
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG1
Target Molecule Chemical
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