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Invitrogen™ VAP-1 Monoclonal Antibody (TK8-18), eBioscience™
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Catalog No. 5017701
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100 μg
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Catalog No. Quantity
50-177-01 100 μg
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Catalog No. 50-177-01 Supplier Invitrogen™ Supplier No. BMS1034
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Description

Mouse Monoclonal Antibody

Description: Lymphocyte binding to vascular endothelium is a prerequisite for the move-ment of immune cells from the blood into lymphoid tissues and into sites ofinflammation. Under inflammatory conditions, cell surface expression ofVAP-1 (vascular adhesion protein-1) which is an endothelial sialoglycoprotein,is induced. VAP-1 is a type II transmembrane protein of 84.6 kDa with a singletransmembrane domain and N and O-glycosylation sites in the extracellulardomain. In vivo, VAP-1 exists predominantly as a 180 kDa homodimer andfunctions both as an enzyme (monoamine oxidase) and an adhesion moleculefor lymphocytes. Applications Tested: ELISA, Western Blotting.

Copper amine oxidases catalyze the oxidative conversion of amines to aldehydes in the presence of copper and quinone cofactor. The product is a major protein on the adipocyte plasma membrane. It has adhesive properties and also has functional monoamine oxidase activity. A pseudogene for this gene has been discribed and is located approximately 9-kb downstream.
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Specifications

Antigen VAP-1
Applications ELISA, Western Blot
Classification Monoclonal
Clone TK8-18
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with no preservative; pH 7.2-7.4
Gene AOC3
Gene Accession No. Q16853
Gene Alias amine oxidase, copper containing 3; amine oxidase, copper containing 3 (vascular adhesion protein 1); Aoc3; Copper amine oxidase; HPAO; Membrane primary amine oxidase; placenta copper monamine oxidase; semicarbazide-sensitive amine oxidase; SSAO; VAP1; VAP-1; Vascular adhesion protein 1; VP97
Gene Symbols AOC3
Host Species Mouse
Purification Method Affinity Chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 8639
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG2a
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