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Invitrogen™ VASN Polyclonal Antibody
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Catalog No. PIPA547258
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100 μg
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Catalog No. Quantity
PIPA547258 100 μg
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Catalog No. PIPA547258 Supplier Invitrogen™ Supplier No. PA547258
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Description

Goat Polyclonal Antibody

Reconstitute at 0.2 mg/mL in sterile PBS.

The VASN gene encodes the protein vasorin, a type I transmembrane protein involved in cellular signaling, vascular development, and tissue repair. Vasorin is characterized by its expression in various tissues, including vascular endothelial cells and smooth muscle cells, where it functions to modulate cell proliferation and differentiation. It plays a significant role in the regulation of vascular remodeling and homeostasis by interacting with signaling molecules like transforming growth factor-beta (TGF-β), thereby influencing processes such as angiogenesis and wound healing. Vasorin is implicated in inhibiting TGF-β signaling pathways, which are crucial for maintaining vascular integrity and preventing excessive fibrosis during tissue repair. Dysregulation of VASN expression can contribute to pathological conditions, including cardiovascular diseases and cancer, where abnormal vascular remodeling and cell proliferation are evident. Research into vasorin continues to explore its functional mechanisms and potential therapeutic applications in diseases characterized by vascular dysregulation and tissue remodeling.
TRUSTED_SUSTAINABILITY

Specifications

Antigen VASN
Applications Western Blot
Classification Polyclonal
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 5% trehalose and No Preservative
Gene VASN
Gene Accession No. Q6EMK4
Gene Alias 2610528G05Rik; Atia; Protein slit-like 2; Slitl2; Slit-like 2; UNQ314/PRO357/PRO1282; VASN; Vasorin
Gene Symbols VASN
Host Species Goat
Immunogen CHO-derived recombinant human Vasorin extracellular domain.
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 114990
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Lyophilized
Isotype IgG
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