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Invitrogen™ VASP Monoclonal Antibody (M277)
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Catalog No. PIMA547684
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100 μL
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Catalog No. Quantity
PIMA547684 100 μL
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Catalog No. PIMA547684 Supplier Invitrogen™ Supplier No. MA547684
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Description

Mouse Monoclonal Antibody

This antibody detects 46 and 50 kDa* proteins corresponding to the apparent molecular mass of VASP on SDS-PAGE immunoblots of human A431, HeLa, and HUVEC.

Vasodilator-stimulated phosphoprotein (VASP) is a member of the Ena-VASP protein family. Ena-VASP family members contain an EHV1 N-terminal domain that binds proteins containing E/DFPPPPXD/E motifs and targets Ena-VASP proteins to focal adhesions. In the mid-region of the protein, family members have a proline-rich domain that binds SH3 and WW domain-containing proteins. Their C-terminal EVH2 domain mediates tetramerization and binds both G and F actin. VASP is associated with filamentous actin formation and likely plays a widespread role in cell adhesion and motility. VASP may also be involved in the intracellular signaling pathways that regulate integrin-extracellular matrix interactions. VASP is regulated by the cyclic nucleotide-dependent kinases PKA and PKG.
TRUSTED_SUSTAINABILITY

Specifications

Antigen VASP
Applications Western Blot, Immunocytochemistry
Classification Monoclonal
Clone M277
Concentration 0.0625 mg/mL
Conjugate Unconjugated
Formulation PBS with 1mg/mL BSA, 50% glycerol and 0.05% sodium azide
Gene VASP
Gene Accession No. P50552
Gene Alias Enah/Vasp-like; I79_012660; Unknown (protein for MGC:127789); vasodilator stimulated phosphoprotein; vasodilator-stimulated phosphoprotein; vasodilator-stimulated phosphoprotein (VASP); VASP
Gene Symbols VASP
Host Species Mouse
Immunogen Clone (M277) was generated from a recombinant protein that includes amino acids from the C-terminal region of human VASP.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 7408
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG1
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