VASP Mouse anti-Human, Clone: OTI1C3, lyophilized, TrueMAB™

Mouse Monoclonal Antibody

Supplier:  OriGene CF502492

Catalog No. 50-166-1386

Description

Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO

Vasodilator-stimulated phosphoprotein (VASP) is a member of the Ena-VASP protein family. Ena-VASP family members contain an EHV1 N-terminal domain that binds proteins containing E/DFPPPPXD/E motifs and targets Ena-VASP proteins to focal adhesions. In the mid-region of the protein, family members have a proline-rich domain that binds SH3 and WW domain-containing proteins. Their C-terminal EVH2 domain mediates tetramerization and binds both G and F actin. VASP is associated with filamentous actin formation and likely plays a widespread role in cell adhesion and motility. VASP may also be involved in the intracellular signaling pathways that regulate integrin-extracellular matrix interactions. VASP is regulated by the cyclic nucleotide-dependent kinases PKA and PKG.

Specifications

• Antigen: VASP
• Classification: Monoclonal
• Conjugate: Unconjugated
• Gene: VASP
• Gene Alias: vasodilator stimulated phosphoprotein
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 7408
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Lyophilized

• Applications: Flow Cytometry, Immunocytochemistry, Immunofluorescence, Western Blot
• Clone: OTI1C3
• Formulation: PBS with 8% trehalose and no preservative; pH 7.3
• Gene Accession No.: P50552
• Gene Symbols: VASP
• Immunogen: Full length human recombit protein of human VASP produced in HEK293T cell.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1