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Invitrogen™ VASP Polyclonal Antibody
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Catalog No. PIPA582211
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100 μL
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PIPA582211 100 μL
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Catalog No. PIPA582211 Supplier Invitrogen™ Supplier No. PA582211
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: PKAESGRSGG GGLMEEMNAM LARRRKATQV GEKTPKDESA NQEEPEARVP AQSESVRRPW EKNSTTLPRM KSSSSVTTSE TQPCTPSSSD YSDLQRVKQE LLEEVKKELQ KVK Highest antigen sequence indentity to the following orthologs: Rat - 82%, Mouse - 85%.

Vasodilator-stimulated phosphoprotein (VASP) is a member of the Ena-VASP protein family. Ena-VASP family members contain an EHV1 N-terminal domain that binds proteins containing E/DFPPPPXD/E motifs and targets Ena-VASP proteins to focal adhesions. In the mid-region of the protein, family members have a proline-rich domain that binds SH3 and WW domain-containing proteins. Their C-terminal EVH2 domain mediates tetramerization and binds both G and F actin. VASP is associated with filamentous actin formation and likely plays a widespread role in cell adhesion and motility. VASP may also be involved in the intracellular signaling pathways that regulate integrin-extracellular matrix interactions. VASP is regulated by the cyclic nucleotide-dependent kinases PKA and PKG.
TRUSTED_SUSTAINABILITY

Specifications

Antigen VASP
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.1 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene VASP
Gene Accession No. P50552, P70460
Gene Alias Enah/Vasp-like; I79_012660; Unknown (protein for MGC:127789); vasodilator stimulated phosphoprotein; vasodilator-stimulated phosphoprotein; vasodilator-stimulated phosphoprotein (VASP); VASP
Gene Symbols VASP
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human VASP. Recombinant protein control fragment (Product #RP-88626).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 22323, 361517, 7408
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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