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  5. Tocris Bioscience™ Vatalanib succinate
  6. 568010

Tocris Bioscience™ Vatalanib succinate

Potent VEGFR inhibitor; also aromatase inhibitor

Supplier:  Tocris Bioscience™ 5680/10

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Catalog No. 568010


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Description

Description

Vatalanib succinate is a potent VEGFR inhibitor (IC50 values are 37 and 77 nM for VEGFR-2 and -1, respectively). Inhibits proliferation, migration and survival of HUVECs in vitro and inhibits growth, vascularization and metastasis of tumors expressing VEGFR in mouse models. Also inhibits PDGFR-β, c-Kit and c-Fms. Potent aromatase inhibitor (IC50 = 50 nM). Orally available.
Specifications

Specifications

N-(4-Chlorophenyl)-4-(4-pyridinylmethyl)-1-phthalazinamine succinate
CGP 79787D, PTK787/ZK222584
VEGF Receptor Inhibitors
464.9
212142-18-2
10 mg
C20H15ClN4.C4H6O4
>99%
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Safety and Handling

Safety and Handling

Recommended Storage : Store at -20°C

SDS
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