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Invitrogen™ VAV1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA599508

Catalog No. PIPA599508


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Description

Description

Antibody detects endogenous levels of total VAV1.

This gene encodes the coiled-coil containing protein optineurin. Optineurin may play a role in normal-tension glaucoma and adult-onset primary open angle glaucoma. Optineurin interacts with adenovirus E3-14.7K protein and may utilize tumor necrosis factor-alpha or Fas-ligand pathways to mediate apoptosis, inflammation or vasoconstriction. Optineurin may also function in cellular morphogenesis and membrane trafficking, vesicle trafficking, and transcription activation through its interactions with the RAB8, huntingtin, and transcription factor IIIA proteins. Alternative splicing results in multiple transcript variants encoding the same protein.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

VAV1
Polyclonal
Unconjugated
VAV1
oncogene vav; p95; p95vav; Proto-oncogene vav; VAV; vav 1 guanine nucleotide exchange factor; vav 1 oncogene; vav guanine nucleotide exchange factor 1; vav oncogene; vav proto-oncogene; VAV1; vav-T
Rabbit
Affinity chromatography
RUO
22324, 25156, 7409
-20°C
Liquid
Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
1 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
P15498, P27870, P54100
VAV1
A synthesized peptide derived from human VAV1(Accession P15498), corresponding to amino acid residues Q148-C198.
100 μL
Primary
Human, Mouse, Rat
Antibody
IgG
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