Invitrogen™ VAV3 Polyclonal Antibody

Catalog No.	Quantity
PIPA590428	100 μL

Catalog No. PIPA590428 Supplier Invitrogen™ Supplier No. PA590428

Description

Rabbit Polyclonal Antibody

Immunogen sequence: DNCGRVNSGE QGTLKLPEKR TNGLRRTPKQ VDPGLPKMQV IRNYSGTPPP ALHEGPPLQL QAGDTVELLK GDAHSLFWQG RNLASGEVGF FPSDAVKPCP CVPKPVDYSC QPWYAGAMER L; Positive Samples: Jurkat, Mouse brain, Mouse lung, Mouse spleen.

This gene is a member of the VAV gene family. The VAV proteins are guanine nucleotide exchange factors (GEFs) for Rho family GTPases that activate pathways leading to actin cytoskeletal rearrangements and transcriptional alterations. This gene product acts as a GEF preferentially for RhoG, RhoA, and to a lesser extent, RAC1, and it associates maximally with the nucleotide-free states of these GTPases. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Specifications

• Antigen: VAV3
• Applications: ELISA, Western Blot, Immunocytochemistry
• Classification: Polyclonal
• Concentration: 1.8 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
• Gene: VAV3
• Gene Accession No.: Q9R0C8, Q9UKW4
• Gene Alias: A530094I06Rik; AA986410; FLJ40431; guanine nucleotide exchange factor VAV3; Idd18.1; RGD1565941; vav 3 guanine nucleotide exchange factor; vav 3 oncogene; vav guanine nucleotide exchange factor 3; Vav3; VAV-3
• Gene Symbols: VAV3
• Host Species: Rabbit
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 560-680 of human VAV3 (NP_0061044).
• Purification Method: Affinity Chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 10451, 57257
• Target Species: Human, Mouse
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG