VCAM-1/CD106 Antibody (1.4C3) - IHC-Prediluted, Novus Biologicals™

Mouse Monoclonal Antibody

Supplier:  Novus Biologicals NBP248171

Catalog No. NBP248171

Description

VCAM-1/CD106 Monoclonal specifically detects VCAM-1/CD106 in Human samples. It is validated for Immunohistochemistry, Immunohistochemistry-Paraffin.

Specifications

• Antigen: VCAM-1/CD106
• Classification: Monoclonal
• Conjugate: Unconjugated
• Formulation: PBS with 0.05% BSA. with 0.05% Sodium Azide
• Gene Symbols: VCAM1
• Immunogen: Stimulated HUVEC cells were used as the immunogen for the VCAM1 (CD106) antibody.
• Quantity: 7 mL
• Research Discipline: Cancer, Mesenchymal Stem Cell Markers, Stem Cell Markers
• Gene ID (Entrez): 7412
• Target Species: Human
• Form: Purified

• Applications: Immunohistochemistry (Paraffin)
• Clone: 1.4C3
• Dilution: Immunohistochemistry-Paraffin
• Gene Alias: CD106, CD106 antigen, DKFZp779G2333, INCAM-100, L1CAM, MGC99561, vascular cell adhesion molecule 1, vascular cell adhesion protein 1, V-CAM 1, VCAM1, VCAM-1
• Host Species: Mouse
• Purification Method: Protein A or G purified
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Test Specificity: Recognizes a protein of 110kDa, identified as CD106 (also known as vascular cell adhesion molecule-1 (VCAM-1) and INCAM-100). CD106 is a member of the Ig superfamily of adhesion molecules and is expressed at high levels on cytokine stimulated vascular endothelial cells, and at minimal levels on un-stimulated endothelial cells. It is also present on follicular and inter-follicular dendritic cells of lymph nodes, myoblasts, and some macrophages. CD106 serves as a ligand for leukocyte integrin (VLA-4 or CD49d/CD29) and mediates cell adhesion of leukocytes to activated endothelium. It plays a role in various immunological and inflammatory responses.
• Content And Storage: Store at 4C.
• Isotype: IgG1 κ