VCAM-1/CD106 Antibody (B-K9), Alexa Fluor™ 350, Novus Biologicals™

Mouse Monoclonal Antibody

Supplier:  Novus Biologicals NBP247864AF350

Catalog No. NP247864A30

Description

VCAM-1/CD106 Monoclonal specifically detects VCAM-1/CD106 in Human, Rat samples. It is validated for Flow Cytometry, Immunocytochemistry/Immunofluorescence, Immunofluorescence.

Specifications

• Antigen: VCAM-1/CD106
• Classification: Monoclonal
• Conjugate: Alexa Fluor 350
• Formulation: 50 mM sodium borate with 0.05% sodium azide
• Gene Symbols: VCAM1
• Immunogen: Activated human umbilical vein endothelial cells (HUVEC)
• Quantity: 0.1 mL
• Primary or Secondary: Primary
• Test Specificity: Recognizes a protein of 110kDa, identified as CD106 (also known as vascular cell adhesion molecule-1 (VCAM-1) and INCAM-100). CD106 is a member of the Ig superfamily of adhesion molecules and is expressed at high levels on cytokine stimulated vascular endothelial cells, and at minimal levels on un-stimulated endothelial cells. It is also present on follicular and inter-follicular dendritic cells of lymph nodes, myoblasts, and some macrophages. CD106 serves as a ligand for leukocyte integrin (VLA-4 or CD49d/CD29) and mediates cell adhesion of leukocytes to activated endothelium. It plays a role in various immunological and inflammatory responses. This monoclonal antibody inhibits the binding of leukocytes to VCAM-1 on stimulated endothelial cells.
• Content And Storage: Store at 4°C in the dark.

• Applications: Flow Cytometry, Immunofluorescence
• Clone: B-K9
• Dilution: Flow Cytometry, Immunofluorescence
• Gene Alias: CD106, CD106 antigen, DKFZp779G2333, INCAM-100, L1CAM, MGC99561, vascular cell adhesion molecule 1, vascular cell adhesion protein 1, V-CAM 1, VCAM1, VCAM-1
• Host Species: Mouse
• Purification Method: Protein A or G purified
• Research Discipline: Cancer, Mesenchymal Stem Cell Markers, Phospho Specific, Stem Cell Markers
• Gene ID (Entrez): 7412.0
• Target Species: Human, Rat
• Isotype: IgG1 κ