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Description
This gene is a member of the Ig superfamily and encodes a cell surface sialoglycoprotein expressed by cytokine-activated endothelium. This type I membrane protein mediates leukocyte-endothelial cell adhesion and signal transduction, and may play a role in the development of artherosclerosis and rheumatoid arthritis. Two alternatively spliced transcripts encoding different isoforms have been described for this gene. [provided by RefSeq]
Specifications
Specifications
| Antigen | VCAM1 |
| Applications | Flow Cytometry, Immunofluorescence, Immunohistochemistry (PFA fixed) |
| Classification | Monoclonal |
| Clone | VCAM1/843 |
| Conjugate | Unconjugated |
| Description | Mouse monoclonal antibody raised against full length recombinant human VCAM1. |
| Dilution | Flow Cytometry (0.5-1 ug/106 cells in 0.1 mL) Immunofluorescence (1-2 ug/mL) Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (0.5-1 ug/mL) The optimal working dilution should be determined by the end user. |
| Formulation | In 10mM PBS. |
| Gene Alias | CD106/DKFZp779G2333/INCAM-100/MGC99561 |
| Gene Symbols | VCAM1 |
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