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Tocris Bioscience™ VCP 171

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Quantity:
10 mg
50 mg
Description
VCP 171 is an adenosine A1 receptor positive allosteric modulator (PAM) (pKB = 5.65, binding cooperativity with NECA 0.68). In absence of orthosteric agonist, VCP171 behaves as an allosteric partial agonist, inhibiting cAMP activity. Inhibits AMPA receptor-mediated evoked excitatory postsynaptic current (eEPSC) amplitude in lamina I and II neurons in a rat partial nerve-injury model of neuropathic pain.
Specifications
Specifications
Chemical Name or Material | [2-Amino-4-[3-(trifluoromethyl)phenyl]-3-thienyl]phenylmethanone |
CAS | 1018830-99-3 |
Quantity | 50 mg |
Target | Adenosine A1 Receptor Modulators |
Molecular Formula | C18H12F3NOS |
Purity | 0.98 |
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