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VDAC1/Porin Mouse anti-Human, Mouse, Rat, Clone: 1E2C7, Proteintech
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Catalog No. 501736776 Shop All Proteintech Group Inc Products
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50-173-6776 150 μL
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Catalog No. 50-173-6776 Supplier Proteintech Group Inc Supplier No. 663451IG150UL
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Description

Mouse Monoclonal Antibody

Voltage-dependent anion channel (VDAC) proteins are abundant, pore-forming proteins belonging to the eukaryotic mitochondrial porins. It was discovered in the mitochondrial outer membrane. It also is expressed in the plasma membrane. At least three different VDAC genes have been identified in vertebrates. VDAC proteins are known to play an essential role in cellular metabolism and in the early stages of apoptosis. For example, VDAC contitutes a major pathway by which metabolites such as ADP/ATP, succinate and citrate are exchanged between the cytosol and mitochondria. And VDAC1 in the plasma membrane establishes a novel level of apoptosis regulation putatively via its redox activity.

Specifications

Antigen VDAC1/Porin
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Monoclonal
Clone 1E2C7
Concentration 0.43 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene VDAC1
Gene Accession No. P21796, Q60932, Q9Z2L0
Gene Alias hVDAC1, Plasmalemmal porin, Porin, PORIN 31 HL, Porin 31HL, Porin 31HM, VDAC, VDAC 1, VDAC1
Gene Symbols VDAC1
Host Species Mouse
Immunogen Peptide
Purification Method Protein A
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 22333, 7416, 83529
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG3
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