VDAC2/VDAC3, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Supplier:  Thermo Scientific PA555444

Catalog No. PIPA555444

Description

The Voltage-Dependant Anion Channel (VDAC) of the outer mitochondrial membrane, a small abundant protein found in all eukaryotic kingdoms, forms a voltage-gated pore when incorporated into planar lipid bilayers. VDAC is also the site of binding of the metabolic enzymes hexokinase and glycerol kinase to the mitochondrion in what may be a significant metabolic regulatory interaction. VDAC3 is involved specifically in translocation of adenine nucleotides through the outer membrane.

Immunogen sequence: TSGHAYTDTG KASGNLETKY KVCNYGLTFT QKWNTDNTLG TEISWENKLA EGLKLTLDTI FVPNTGKKSG KLKASYKRDC FSVGSNVDID FSGPTIYGWA VLAFEGWLAG YQMSFDTAKS KLSQNNFALG YKAADFQLHT HHighest antigen sequence identity to the following orthologs: Mouse - 99%, Rat - 96%.

Specifications

• Antigen: VDAC2/VDAC3
• Classification: Polyclonal
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: P45880, Q9Y277
• Gene Symbols: VDAC2, VDAC3
• Immunogen: Recombinant protein corresponding to Human VDAC2/VDAC3
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

• Applications: Immunocytochemistry, Immunofluorescence, Immunohistochemistry
• Conjugate: Unconjugated
• Gene: VDAC3
• Gene Alias: VDAC2, VDAC3, RP11-375G3.1, FLJ23841, Voltage-dependent anion-selective channel protein 2, Voltage-dependent anion-selective channel protein 3, hVDAC-2, hVDAC-3
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 7417, 7419
• Content And Storage: Store at 4°C short term. Store at −20°C long term. Avoid freeze/thaw cycles.
• Form: Liquid

Research Use Only