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VDCC-L alpha Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501984980
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50-198-4980 100 μL
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Catalog No. 50-198-4980 Supplier Bioss Supplier No. BS2806R
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Description

Rabbit Polyclonal Antibody

CACNA1C encodes an alpha-1 subunit of a voltage-dependent calcium channel. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization. The alpha-1 subunit consists of 24 transmembrane segments and forms the pore through which ions pass into the cell. The calcium channel consists of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. There are multiple isoforms of each of these proteins, either encoded by different genes or the result of alternative splicing of transcripts. The protein encoded by CACNA1C binds to and is inhibited by dihydropyridine. Alternative splicing results in many transcript variants encoding different proteins.

Specifications

Antigen VDCC-L alpha
Applications Immunofluorescence, Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene CACNA1C
Gene Accession No. Q13936
Gene Alias brain class C; CACB; CaCB receptor; CACB-receptor; Cach2; CACH2C; CACH3; Cacn2; CACN4; CACNA 1D; Cacna1c; CACNL1A1; CACNL1A2; calcium channel; calcium channel voltage-dependent alpha1c subunit; calcium channel, cardic dihydropyridine-sensitive, alpha-1 subunit; Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle; calcium channel, voltage-dependent, alpha 1C subunit; calcium channel, voltage-dependent, L type, alpha 1C subunit; calcium voltage-gated channel subunit alpha1 C; cardiac L-type calcium channel; CaV1.2; CCHL1A1; D930026N18Rik; DHP receptor; DHPR, alpha-1 subunit; I79_006562; long-NT; LQT8; LTCC; L-type calcium channel alpha-1 subunit; MBC; MELC-CC; MGC120730; Mouse brain class C; neuronal voltage-gated calcium channel alpha 1C subunit; Rat brain class C; RATIVS302; RBC; skeletal muscle-specific calcium channel; smooth muscle calcium channel blocker; Smooth muscle calcium channel blocker receptor; TS; voltage-dependent L-type Ca2+ channel alpha 1 subunit; Voltage-dependent L-type calcium channel subunit alpha-1C; Voltage-gated calcium channel subunit alpha Cav1.2; voltage-gated L-type calcium channel Cav1.2 alpha 1 subunit, splice variant 10*
Gene Symbols CACNA1C
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide derived from human VDCC-L alpha.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 775
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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