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Invitrogen™ VE-cadherin Monoclonal Antibody (GT1369)
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Catalog No. PIMA546904
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100 μL
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PIMA546904 100 μL
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Catalog No. PIMA546904 Supplier Invitrogen™ Supplier No. MA546904
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Mouse Monoclonal Antibody

Store as concentrated solution. Centrifuge briefly prior to opening vial.

VE-cadherin is a member of the cadherin superfamily that is located in a six-cadherin cluster in a region on the long arm of chromosome 16 and is involved in loss of heterozygosity events in breast and prostate cancer. VE-cadherin protein is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Functioning as a classic cadherin by imparting to cells the ability to adhere in a homophilic manner, VE-cadherin may play an important role in endothelial cell biology through control of the cohesion and organization of the intercellular junctions. An alternative splice variant has been described but the full length sequence of VE-cadherin has not been determined.
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Specifications

Antigen VE-cadherin
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Monoclonal
Clone GT1369
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 20% glycerol and no preservative; pH 7
Gene CDH5
Gene Accession No. P33151
Gene Alias 7B4; 7B4 antigen; 7B4/cadherin-5; AA408225; cadherin 5; cadherin 5, type 2 (vascular endothelium); cadherin 5, type 2, VE-cadherin (vascular endothelium); cadherin 5, type 2, VE-cadherin (vascular epithelium); cadherin-5; cadherin-5; cd144 antigen; VE cadherin; Cd144; cd144 antigen; CDH5; cell-cell adhesion protein; endothelial-specific cadherin; vascular endothelial cadherin; vascular endothelial cadherin precursor; Vec; VEcad; VE-Cad; VE-cadherin; VECD
Gene Symbols CDH5
Host Species Mouse
Immunogen Synthetic peptide encompassing a sequence within the Extracellular domain of human VE-cadherin. The exact sequence is proprietary.
Purification Method Protein G
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1003
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1
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WARNING: Cancer - www.P65Warnings.ca.gov
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