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Invitrogen™ VE-cadherin Polyclonal Antibody
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Catalog No. PIPA517401
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100 μL
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PIPA517401 100 μL
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Catalog No. PIPA517401 Supplier Invitrogen™ Supplier No. PA517401
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Description

Rabbit Polyclonal Antibody

It is not recommended to aliquot this antibody. This antibody is not cross-reactive with other cadherin family members.

VE-cadherin is a member of the cadherin superfamily that is located in a six-cadherin cluster in a region on the long arm of chromosome 16 and is involved in loss of heterozygosity events in breast and prostate cancer. VE-cadherin protein is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Functioning as a classic cadherin by imparting to cells the ability to adhere in a homophilic manner, VE-cadherin may play an important role in endothelial cell biology through control of the cohesion and organization of the intercellular junctions. An alternative splice variant has been described but the full length sequence of VE-cadherin has not been determined.
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Specifications

Antigen VE-cadherin
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 22 μg/mL
Conjugate Unconjugated
Formulation 0.01M HEPES with 50% glycerol, 100μg/mL BSA, 0.15M NaCl and no preservative; pH 7.5
Gene CDH5
Gene Accession No. P33151, Q6URK6
Gene Alias 7B4; 7B4 antigen; 7B4/cadherin-5; AA408225; cadherin 5; cadherin 5, type 2 (vascular endothelium); cadherin 5, type 2, VE-cadherin (vascular endothelium); cadherin 5, type 2, VE-cadherin (vascular epithelium); cadherin-5; cadherin-5; cd144 antigen; VE cadherin; Cd144; cd144 antigen; CDH5; cell-cell adhesion protein; endothelial-specific cadherin; vascular endothelial cadherin; vascular endothelial cadherin precursor; Vec; VEcad; VE-Cad; VE-cadherin; VECD
Gene Symbols CDH5
Host Species Rabbit
Immunogen Synthetic peptide corresponding to the carboxy-terminus of human VE-cadherin.
Purification Method Antigen affinity chromatography, Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1003, 414735
Target Species Bovine, Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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