Invitrogen™ VEGF-165 Polyclonal Antibody

Goat Polyclonal Antibody

Supplier:  Invitrogen™ PA547103

Catalog No. PIPA547103

Description

In Western blots, less than 2% cross-reactivity with recombinant human VEGF165, recombinant mouse VEGF164, and recombinant rat VEGF164 (under non-reducing conditions) is observed. Reconstitute at 0.2 mg/mL in sterile PBS. Endoxin level is <0.10 EU per 1 μg of the antibody by the LAL method.

The vascular endothelial growth factor (VEGF) family currently includes VEGF-A, VEGF-B, VEGF-C, VEGF-D, VEGF-E, and PIGF. VEGF and its receptor system have been shown to be the fundamental regulators in the cell signaling of angiogenesis. Most tumors have the absolute requirement of angiogenesis and VEGF has been described as the most potent angiogenic cytokine linked to this process. To date 5 different isoforms of VEGF have been described. These isoforms are generated as the result of alternative splicing from a single VEGF gene. These various isoforms have been shown to bind to two tyrosine-kinase receptors flt-1 (VEGFR-1) and flk-1/KDR (VEGFR-2), which have been found to be expressed almost exclusively on endothelial cells.

Specifications

• Antigen: VEGF-165
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: vegfaa
• Gene Alias: H-VEGF-165; MVCD1; M-VEGF-165; vascular endothelial growth factor 165b; vascular endothelial growth factor A; vascular endothelial growth factor A121; vascular endothelial growth factor A165; vascular permeability factor; VEGF; VEGF164; VEGF165; Vegfa; VEGF-A; VPF
• Host Species: Goat
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 30682
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Lyophilized

• Applications: Neutralization, Western Blot
• Concentration: 0.2 mg/mL
• Formulation: PBS with 5% trehalose and No Preservative
• Gene Accession No.: O73682
• Gene Symbols: VEGFAA
• Immunogen: Sf 21-derived recombinant zebrafish VEGF165 Ala24-Arg188.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Zebrafish
• Product Type: Antibody
• Isotype: IgG