Invitrogen™ VEGF Receptor 1/2 Polyclonal Antibody

Catalog No.	Quantity
APPA6612	100 μL

Catalog No. APPA6612 Supplier Invitrogen™ Supplier No. PA116612

Description

Rabbit Polyclonal Antibody

The target sequence has 100% sequence homology with mouse and rat.

Receptors for VEGF, VEGFB and PGF have a tyrosine-protein kinase activity. The VEGF-kinase ligand/receptor signaling system plays a key role in vascular development and regulation of vascular permeability. VEGF and its high-affinity binding receptors, the tyrosine kinases FLK1 and FLT1, are thought to be important for the development of embryonic vasculature. It has been shown that an alternately spliced form of FLT1 produces a soluble protein, termed sFLT1, which binds vascular endothelial growth factor with high affinity, playing an inhibitory role in angiogenesis.

Specifications

• Antigen: VEGF Receptor 1/2
• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Classification: Polyclonal
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 0.02% sodium azide
• Gene: FLT1
• Gene Accession No.: O08775, P17948, P35968, P53767
• Gene Alias: 6130401C07; AI323757; CD309; Embryonic receptor kinase 2; Emrk2; Fetal liver kinase 1; fetal liver kinase-1; Flk1; FLK-1; FLK1 kinase insert domain receptor (a type III receptor tyrosine kinase) (VEGF receptor 2); FLK1 kinase insert domain receptor (VEGF receptor 2); FLT; Flt1; FLT-1; fms related tyrosine kinase 1; FMS-like tyrosine kinase 1; FMS-related tyrosine kinase 1; Fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor); FRT; KDR; kinase insert domain protein receptor; kinase insert domain receptor; kinase insert domain receptor (a type III receptor tyrosine kinase); kinase NYK; Krd-1; Ly73; Protein-tyrosine kinase receptor flk-1; sFlt1; soluble vascular endothelial growth factor receptor 2; soluble VEGFR 1; soluble VEGFR2; sVEGFR 1; sVEGFR-2; tyrosine kinase growth factor receptor; tyrosine-protein kinase FRT; Tyrosine-protein kinase receptor FLT; vascular endothelial growth factor receptor 1; Vascular endothelial growth factor receptor 2; vascular endothelial growth factor receptor- 2; vascular endothelial growth factor receptor-1; vascular endothelial growth factor receptor-2; vascular endothelial growth factor receptor-3; vascular permeability factor receptor; VEGF R1; VEGF receptor-2; VEGFR; VEGFR 1; Vegfr1; VEGFR-1; VEGFR2; Vegfr-2
• Gene Symbols: FLT1, KDR
• Host Species: Rabbit
• Immunogen: A synthetic peptide made to an internal region of the mouse VEGF Receptor 1 protein (between residues 800-900).
• Purification Method: Antigen affinity chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 2321, 25589, 3791, 54251
• Target Species: Human, Rat
• Content And Storage: 4°C, do not freeze
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG