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Invitrogen™ VEGF Receptor 3 Monoclonal Antibody (4H4)
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Catalog No. PIMA515651
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100 μL
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Catalog No. Quantity
PIMA515651 100 μL
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Catalog No. PIMA515651 Supplier Invitrogen™ Supplier No. MA515651
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Description

Mouse Monoclonal Antibody

MA5-15651 targets FLT4 in indirect ELISA, WB applications and shows reactivity with Human samples. The MA5-15651 immunogen is purified recombinant fragment of human FLT4 expressed in E. Coli.. MA5-15651 detects FLT4 which has a predicted molecular weight of approximately 145kDa.

Vascular endothelial growth factor is a key regulator of blood vessel development in embryos and angiogenesis in adult tissues. Unlike VEGF, the related VEGFC stimulates the growth of lymphatic vessels through its specificl ymphatic endothelial receptor VEGFR-3. In 1998, Dumont showed that targeted inactivation of the VEGFR-3 gene in mice resulted in defective blood vessel development in early embryos. Vasculogenesis and angiogenesis occurred, but large vessels became abnormally organized with defective lumens, leading to fluid accumulation in the pericardial cavity and cardiovascular failure at embryonic day 9.5. Thus, VEGFR3 has an essential role in the development of theembryonic cardiovascular system before the emergence of the lymphatic vessels.
TRUSTED_SUSTAINABILITY

Specifications

Antigen VEGF Receptor 3
Applications ELISA, Western Blot, Immunocytochemistry
Classification Monoclonal
Clone 4H4
Concentration Conc. Not Determined
Conjugate Unconjugated
Formulation ascites with 0.03% sodium azide
Gene FLT4
Gene Accession No. P35916
Gene Alias AI323512; Chy; chylous ascites; Flt4; FLT-4; FLT41; fms related tyrosine kinase 4; FMS-like tyrosine kinase 4; fms-related tyrosine kinase 4; LMPH1A; PCL; receptor protein tyrosine kinase; soluble VEGFR 3; sVEGFR 3; tyrosine-protein kinase receptor FLT4; Vascular endothelial growth factor receptor 3; vascular endothelial growth factor receptor-3; VEGF R3; VEGFR3; VEGFR-3
Gene Symbols FLT4
Host Species Mouse
Immunogen Purified recombinant fragment of human FLT4 expressed in E. Coli.
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 2324
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1
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