VEGFR1/Flt-1 Antibody (FLT1/658), Novus Biologicals™

Mouse Monoclonal Antibody

Catalog Number	Mfr. No.	Quantity
NBP232908F	Novus Biologicals NBP2329080.02MG	0.02 mg
NBP232908A	Novus Biologicals NBP2329080.1MG	0.1 mg
NBP232908B	Novus Biologicals NBP2329080.2MG	0.2 mg

Description

VEGFR1/Flt-1 Monoclonal specifically detects VEGFR1/Flt-1 in Human samples. It is validated for Flow Cytometry, Immunocytochemistry/Immunofluorescence, Functional, Immunofluorescence.

Specifications

• Antigen: VEGFR1/Flt-1
• Dilution: Flow Cytometry 0.5-1ug/million cells in 0.1ml, SDS-Page, Immunofluorescence 1-2ug/ml
• Classification: Monoclonal
• Form: Purified
• Regulatory Status: RUO
• Target Species: Human
• Gene Accession No.: P17948
• Gene ID (Entrez): 2321
• Immunogen: Recombinant human VEGF-R1 protein
• Primary or Secondary: Primary
• Content And Storage: Store at 4C.

• Clone: FLT1/658
• Applications: Flow Cytometry, SDS-Page, Immunofluorescence
• Conjugate: Unconjugated
• Host Species: Mouse
• Research Discipline: Angiogenesis, Cancer, Cellular Markers, Endothelial Cell Markers, HIF Target Genes, Hypoxia, Phospho Specific, Signal Transduction, Stem Cell Markers, Tumor Suppressors, Tyrosine Kinases
• Formulation: PBS with 0.05% BSA. with 0.05% Sodium Azide
• Gene Alias: EC 2.7.10, EC 2.7.10.1, FLT, FLT-1, Fms-like tyrosine kinase 1, fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascularpermeability factor receptor), FRT, Tyrosine-protein kinase FRT, Tyrosine-protein kinase receptor FLT, vascular endothelial growth factor receptor 1, Vascular permeability factor receptor, VEGFR1, VEGFR-1
• Gene Symbols: FLT1
• Isotype: IgG1 κ
• Purification Method: Protein A purified
• Test Specificity: Three cell membrane receptor tyrosine kinases, Flt-1 (also designated VEGF-R1), Flk-1 (also designated VEGF-R2) and Flt-4, putatively involved in the growth of endothelial cells, are characterized by the presence of seven immunoglobulin-like sequences in their extracellular domain. These receptors exhibit high degrees of sequence relatedness to each other as well as lesser degrees of relatedness to the class III receptors including CSF-1/Fms, PDGR, SLFR/Kit and Flt-3/Flk-2. Two members of this receptor class, Flt-1 and Flk-1, have been shown to represent high affinity receptors for vascular endothelial growth factors (VEGFs). On the basis of structural similarity to Flt-1 and Flk-1, it has been speculated that Flt-4 might represent a third receptor for either VEGF or a VEGF-related ligand.