Invitrogen™ Venezuelan Equine Encephalitis Virus NSP1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5144447

Catalog No. FEPA5144447

Description

Venezuelan Equine Encephalitis Virus NSP1 Polyclonal Antibody for Western Blot, ELISA

Venezuelan equine encephalitis virus (VEEV) is a member of genus Alphavirus in the family Togaviridae VEEV encodes four nonstructural proteins (nsP1, nsP2, nsP3 and nsP4) and five structural proteins (capsid (C), envelope (E) 3, E2, 6k, and E1) The Nsp1 gene of VEEV contains a 51-nt conserved sequence element (CSE) that is essential for virus replication Mutation or deletion of CSE results in loss of infectivity of VEEV, probably due to inefficient recognition of the viral RNA core promoter element by the virus replication complex Nsp1 functions as a methyltransferase and guanylylation enzyme, two properties needed for the 5' capping of VEEV genomic RNA [PMID: 30781656].

Specifications

• Antigen: Venezuelan Equine Encephalitis Virus NSP1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene Alias: VEEV NSP1
• Immunogen: Recombinant Venezuelan equine encephalitis virus (strain Trinidad donkey) (VEEV) Non-structural polyprotein (1-288aa).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Content And Storage: -20°C or -80°C if preferred
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 1.366 mg/mL
• Formulation: PBS with 50% glycerol and 0.03% Proclin 300; pH 7.4
• Host Species: Rabbit
• Purification Method: Protein G
• Regulatory Status: RUO
• Target Species: Virus
• Product Type: Antibody
• Isotype: IgG