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Invitrogen™ VGAT Polyclonal Antibody
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Catalog No. PIPA596231
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100 μL
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PIPA596231 100 μL
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Catalog No. PIPA596231 Supplier Invitrogen™ Supplier No. PA596231
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Description

Rabbit Polyclonal Antibody

Positive Samples: Mouse spinal cord, Mouse brain; Cellular Location: Cytoplasmic vesicle membrane, Multi-pass membrane protein Immunogen sequence: MATLLRSKLS NVATSVSNKS QAKMSGMFAR MGFQAATDEE AVGFAHCDDL DFEHRQGLQM DILKAEGEPC GDEGAEAPVE GDIHYQRGSG APLPPSGSKD QVGGGGEFGG HDKPKITAWE AGWNVTNAIQ GMFVLGLPYA ILHGGYLGLF LIIFAAVVCC YTGKILIACL YEENEDGEVV RVRDSYVAIA NACCAPRFPT LGGRVVNVAQ IIELVMTCIL YVVVSGNLMY NSFPGLPVSQ KSWSIIATAV LLPCAFLKNL KAVSKFSLLC TLAHFVINIL VIAYCLSRAR DWAWEKVKFY IDVKKFPISI GIIVFSYTSQ IFLPSLEGNM QQPSEFHCMM NWTHIAACVL KGLFALVAYL TWADETKEVI TDNLPGSIRA VVNIFLVAKA LLSYPLPFFA AVEVLEKSLF QEGSRAFFPA CYSGDGRLKS WGLTLRCALV VFTLLMAIYV PHFALLMGLT GSLTGAGLCF LLPSLFHLRL LWRKLLWHQV FFDVAIFVIG GICSVSGFVH SLEGLIEAYR TNAED.

The Vesicular GABA Amino Acid Transporter (VGAT) is responsible for transport of the inhibitory neurotransmitter into synaptic vesicles (McIntire et al., 1997). The VGAT protein (also known as the Vesicular Inhibitory Amino Aid Transporter or VIAAT) is expressed in synaptic vesicles of both glycine and GABAergic synapses throughout the CNS (Chaudhry et al., 1998). Expression of the VGAT protein changes during development and also in response to patterns of neuronal activity (De et al., 2005).
TRUSTED_SUSTAINABILITY

Specifications

Antigen VGAT
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 2.79 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene SLC32A1
Gene Accession No. O35458, O35633, Q9H598
Gene Alias GABA and glycine transporter; GVAT; hVIAAT; mVGAT; mVIAAT; R75019; rGVAT; SLC32A1; solute carrier family 32 (GABA vesicular transporter), member 1; solute carrier family 32 member 1; vasicular inhibitory amino acid transporter 10D; vesicular GABA transporter; Vesicular inhibitory amino acid transporter; Vgat; Viaat
Gene Symbols SLC32A1
Host Species Rabbit
Immunogen Recombinant protein (or fragment).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 140679, 22348, 83612
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

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