Invitrogen™ VGAT Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA14701

Catalog No. APP4701

Description

This antibody is predicted to react with bovine, canine and non-human primate based on 100% sequence homology. In Western blot, this antibody is specific for the ~53 kDa VGAT protein.

The Vesicular GABA Amino Acid Transporter (VGAT) is responsible for transport of the inhibitory neurotransmitter into synaptic vesicles (McIntire et al., 1997). The VGAT protein (also known as the Vesicular Inhibitory Amino Aid Transporter or VIAAT) is expressed in synaptic vesicles of both glycine and GABAergic synapses throughout the CNS (Chaudhry et al., 1998). Expression of the VGAT protein changes during development and also in response to patterns of neuronal activity (De et al., 2005).

Specifications

• Antigen: VGAT
• Classification: Polyclonal
• Formulation: 0.01M HEPES with 100 μg/mL BSA, 50% glycerol, 0.15M NaCl and no preservative; pH 7.5
• Gene Accession No.: O35458, O35633
• Gene Symbols: SLC32A1
• Immunogen: Synthetic peptide corresponding to the N-terminal region of rat SLC32A1 conjugated to KLH.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Mouse, Rat, Chicken, Frog
• Product Type: Antibody
• Isotype: IgG

• Applications: Immunohistochemistry, Western Blot, Immunocytochemistry
• Conjugate: Unconjugated
• Gene: SLC32A1
• Gene Alias: GABA and glycine transporter; GVAT; hVIAAT; mVGAT; mVIAAT; R75019; rGVAT; SLC32A1; solute carrier family 32 (GABA vesicular transporter), member 1; solute carrier family 32 member 1; vasicular inhibitory amino acid transporter 10D; vesicular GABA transporter; Vesicular inhibitory amino acid transporter; Vgat; Viaat
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 22348, 419167, 83612
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

Safety and Handling

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