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Invitrogen™ VGF Monoclonal Antibody (9#)
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Catalog No. PIMA541690
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200 μL
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PIMA541690 200 μL
PIMA543702 20 μL
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Catalog No. PIMA541690 Supplier Invitrogen™ Supplier No. MA541690
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Mouse Monoclonal Antibody

VGF Monoclonal Antibody for IHC (P), Western Blot

VGF was initially identified as a rapidly regulated gene product in nerve growth factor-treated PC12 cells. This protein is synthesized in neurons in the central and peripheral nervous system as well as in the pituitary, adrenal medulla, endocrine cells of the stomach, and pancreatic beta cells. VGF is thought to be involved in organism energy balance and regulation of homeostasis as mice lacking this gene show deficits in these areas. More recent results suggest that VGF is upregulated by brain-derived neurotrophic factor (BDNF) and can stimulate the proliferation of hippocampal progenitor cells and produce antidepressant-like behavioral effects, suggesting that this pathway may be a suitable target for therapeutic treatments.
TRUSTED_SUSTAINABILITY

Specifications

Antigen VGF
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Monoclonal
Clone 9#
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.05% ProClin 300; pH 7.4
Gene VGF
Gene Accession No. O15240, P20156
Gene Alias Antimicrobial peptide VGF[554-577]; Gm1052; NERP-1; NERP-2; Neuroendocrine regulatory peptide-1; Neuroendocrine regulatory peptide-2; neuro-endocrine specific protein VGF; Neurosecretory protein VGF; SCG7; SgVII; Vgf; VGF nerve growth factor inducible; VGF(180-194); VGF(24-63); VGF(375-407); VGF8a protein; VGF-derived peptide AQEE-30; VGF-derived peptide HFHH-10; VGF-derived peptide LQEQ-19; VGF-derived peptide TLQP-11; VGF-derived peptide TLQP-21; VGF-derived peptide TLQP-30; VGF-derived peptide TLQP-62
Gene Symbols VGF
Host Species Mouse
Immunogen Recombinant protein VGF Nerve Growth Factor Inducible. The antigen corresponds to amino acid range 330-449 of the target protein.
Purification Method Protein A/G
Quantity 200 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 102163755, 110259887, 29461, 7425
Target Species Human, Pig, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG2b κ
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