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Tocris Bioscience™ VHF 543, amine

Catalog No. 80755
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5 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

DCAF1 WD40 ligand with terminal amine for onward chemistry

VHF 543, amine is a potent ligand for the WD40 repeat domain (WDR) of DCAF1 (Kd = 31 nM measured by surface plasmon resonance). VHF 543, amine is supplied with a primary amine functional handle, for ready conjugation to a linker/target protein ligand.

Please contact us for SD files of our available Degrader Building Blocks.

PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license.

Specifications

Chemical Name or Material 1-(4-(4-((2-Aminoethyl)amino)-2-(1-(4-chlorophenyl)cyclohexyl)quinazolin-7-yl)piperazin-1-yl)ethan-1-one
CAS 3053860-67-3
Quantity 5 mg
Target Degrader Building Blocks
Molecular Formula C28H35ClN6O
Purity 0.98
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