Invitrogen™ Villin Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA522072

Catalog No. PIPA522072

Description

Recommended positive controls: HepG2, mouse kidney, rat kidney. Predicted reactivity: Mouse (89%), Rat (89%), Bovine (90%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Villin is part of cytoskeleton associated with the microvillar actin core bundle of gastrointestinal and renal brush border. It can interact with actin in a Ca2+ and phosphoinositide-regulated manner. Villin is a very specific marker for adenocarcinomas of the gastrointestinal tract and the pancreas. It is also expressed in some Merkel cell tumor and adenocarcinoma of the lung, prostate, ovarian and kidney.

Specifications

• Antigen: Villin
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: VIL1
• Gene Alias: D2S1471; OTTHUMP00000207159; Vil; Vil1; villin 1; villin-1
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 22349, 316521, 7429
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 0.85 mg/mL
• Formulation: PBS with 20% glycerol and 0.025% ProClin 300; pH 7
• Gene Accession No.: P09327, Q62468
• Gene Symbols: VIL1
• Immunogen: Recombinant protein fragment contain a sequence corresponding to a region within amino acids 7 and 246 (P09327) of Villin.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG