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Invitrogen™ Vimentin Recombinant Rabbit Monoclonal Antibody (001)
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Catalog No. PIMA541057
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Quantity:
100 μL
Catalog No. Quantity
PIMA541057 100 μL
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Catalog No. PIMA541057

Supplier: Invitrogen™ MA541057

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Description

Rabbit Recombinant Monoclonal Antibody

Vimentin Recombinant Monoclonal Antibody for Western Blot, IHC (P)

Vimentin is a developmentally regulated intermediate filament protein (IFP) found in cells of mesenchymal origin. It is believed to be involved with the intracellular transport of proteins between the nucleus and plasma membrane. Unlike other IFP proteins, vimentin is expressed, along with desmin, during the early stages of cellular development. During the development process, vimentin is exchanged for new, tissue-specific IFPs. Vimentin has been implicated to be involved in the rate of steroid synthesis via its role as a storage network for steroidogenic cholesterol containing lipid droplets. Vimentin phosphorylation by a protein kinase causes the breakdown of intermediate filaments and activation of an ATP and myosin light chain dependent contractile event. This results in cytoskeletal changes that facilitate the interaction of the lipid droplets within mitochondria, and subsequent transport of cholesterol to the organelles leading to an increase in steroid synthesis.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Vimentin
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Recombinant Monoclonal
Clone 001
Conjugate Unconjugated
Formulation PBS with no preservative
Gene Vim
Gene Accession No. P08670
Gene Alias cb28; class-III intermediate microfilament; CTRCT30; epididymis luminal protein 113; FLJ36605; HEL113; intermediate filament; intermediate filament protein; RP11-124N14.1; similar to vimentin; VIM; VIME; Vimentin; vimentin C-terminus
Gene Symbols Vim
Host Species Rabbit
Immunogen A synthetic peptide corresponding to the center region of the Human Vimentin/VIM.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 7431
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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