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VISTA Monoclonal Antibody (B7H5DS8), APC, eBioscience™, Invitrogen™

Mouse Monoclonal Antibody

$184.00 - $437.00

Specifications

Antigen VISTA
Clone B7H5DS8
Concentration 5 μL/Test
Applications Flow Cytometry
Classification Monoclonal
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Products 2
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
17-108-841
Encompass_Preferred
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Invitrogen™
17108841
25 Tests
Each for $184.00
Only null left
Add to Cart
 
17-108-842
Encompass_Preferred
View Documents
Invitrogen™
17108842
100 Tests
Each for $437.00
Only null left
Add to Cart
 
Description

Description

Description: This B7H5DS8 monoclonal antibody recognizes human VISTA also known as B7-H5 or PD-H1. This clone has been tested and shown not to cross-react with human B7-H4, B7-H5 and B7-H7. This B7H5DS8 antibody will work in flow cytometry only on live and not paraformaldehyde-fixed cells. Applications Reported: This B7H5DS8 antibody has been reported for use in flow cytometric analysis. Applications Tested: This B7H5DS8 antibody has been tested by flow cytometric analysis of normal human peripheral blood cells. This may be used at 5 μL (0.25 μg) per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest. Excitation: 633-647 nm; Emission: 660 nm; Laser: Red Laser

VISTA (V-domain Ig containing suppressor of T-cell activation), also known as B7-H5 or PD-1H, is a product of the VSIR gene. Although VISTA bears sequence homology to PD-L1 it has a different expression pattern. In both mouse and humans, VISTA is expressed predominantly on hematopoietic cells with the highest densities on myeloid cells, and lower levels on T cells. It is usually absent on B cells. VISTA expressed by antigen presenting cells has been shown to directly suppress proliferation and cytokine production of CD4 and CD8 T cells, making it a target for cancer immunotherapy. The reported ligands of VISTA include CD28H, VSIG-3 and VSIG-8.
Specifications

Specifications

VISTA
5 μL/Test
Monoclonal
Liquid
RUO
PBS with 0.09% sodium azide; pH 7.2
4632428N05Rik; B7H5; B7-H5; C10orf54; C1H10orf54; C28H10orf54; C4H10orf54; chromosome 10 open reading frame 54; DD1alpha; Death Domain1alpha; Dies1; differentiation of ESCs 1; GI24; PD-1H; PDCD1 homolog; PD-H1; platelet receptor Gi24; PP2135; RIKEN cDNA 4632428N05 gene; SISP1; sisp-1; Stress-induced secreted protein-1; UNQ730/PRO1412; V-domain Ig suppressor of T cell activation; VISTA; V-set domain-containing immunoregulatory receptor; V-set immunoregulatory receptor; VSIR; V-type immunoglobulin domain-containing suppressor of T-cell activation
VSIR
IgG1 κ
Affinity chromatography
Antibody
B7H5DS8
Flow Cytometry
APC
Mouse
Human
Q9H7M9
64115
VISTA-Fc protein.
Primary
4°C, store in dark, DO NOT FREEZE!
VSIR
Videos
SDS
Documents

Documents

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