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Invitrogen™ Vitronectin Monoclonal Antibody (A27)
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Catalog No. CSI0042702
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400 μL
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CSI0042702 400 μL
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Catalog No. CSI0042702 Supplier Invitrogen™ Supplier No. CSI0042702
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Mouse Monoclonal Antibody

CSI 004-27-02 is highly specific for vitronectin. There is no evidence for cross-reactivity with other connective tissue proteins (fibronectin, elastin, collagen, laminin). CSI 004-27-02 cross-reacts with sheep vitronectin, no reactivity with human or horse. CSI 004-27-02 has been successfully used in ELISA, Western blotting and Immunohistochemistry techniques. CSI 004-27-02 is suitable for ELISA, immunoblotting and immunostaining of frozen PLP-fixed sections of bovine tissues. The antibody can be used as an affinity purification reagent of vitronectin from bovine plasma or serum and to quantitatively deplete plasma or serum of vitronectin. It can also be used to probe vitronectin conformation. NOTE: Concentration is lot-dependent and can vary from 0.85-1.15 mg/mL.

VTN is a member of the pexin family. This protein is found in serum and tissues and promotes cell adhesion and spreading, inhibits the membrane-damaging effect of the terminal cytolytic complement pathway, and binds to several serpin serine protease inhibitors. The protein is a secreted protein and exists in either a single chain form or a clipped, two chain form held together by a disulfide bond.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Vitronectin
Applications ELISA, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot
Classification Monoclonal
Clone A27
Concentration 1.08 mg/mL
Conjugate Unconjugated
Formulation PBS with 15 mM sodium azide; pH 7.4
Gene VTN
Gene Accession No. 0
Gene Alias Aa1018; AI256434; complement S-protein; epibolin; extracellular matrix protein; glycoprotein 66; serum spreading factor; serum-spreading factor; somatomedin B; Somatomedin-B; S-protein; V75; Vitronectin; vitronectin (serum spreading factor, somatomedin B, complement S-protein); Vitronectin V10 subunit; Vitronectin V65 subunit; VN; VNT; VTN
Gene Symbols VTN
Host Species Mouse
Immunogen Lysed bovine corneal endothelial cells and extracellular matrix.
Purification Method Protein A/G
Quantity 400 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 101119231, 507525
Target Species Bovine, Sheep
Content And Storage 4°C, store in dark
Product Type Antibody
Form Liquid
Isotype IgG1 κ
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WARNING: Reproductive Harm - www.P65Warnings.ca.gov
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