Invitrogen™ Vitronectin Monoclonal Antibody (A27)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ CSI0042702

Catalog No. CSI0042702

Description

CSI 004-27-02 is highly specific for vitronectin. There is no evidence for cross-reactivity with other connective tissue proteins (fibronectin, elastin, collagen, laminin). CSI 004-27-02 cross-reacts with sheep vitronectin, no reactivity with human or horse. CSI 004-27-02 has been successfully used in ELISA, Western blotting and Immunohistochemistry techniques. CSI 004-27-02 is suitable for ELISA, immunoblotting and immunostaining of frozen PLP-fixed sections of bovine tissues. The antibody can be used as an affinity purification reagent of vitronectin from bovine plasma or serum and to quantitatively deplete plasma or serum of vitronectin. It can also be used to probe vitronectin conformation. NOTE: Concentration is lot-dependent and can vary from 0.85-1.15 mg/mL.

VTN is a member of the pexin family. This protein is found in serum and tissues and promotes cell adhesion and spreading, inhibits the membrane-damaging effect of the terminal cytolytic complement pathway, and binds to several serpin serine protease inhibitors. The protein is a secreted protein and exists in either a single chain form or a clipped, two chain form held together by a disulfide bond.

Specifications

• Antigen: Vitronectin
• Classification: Monoclonal
• Concentration: 1.08 mg/mL
• Formulation: PBS with 15 mM sodium azide; pH 7.4
• Gene Accession No.: 0
• Gene Symbols: VTN
• Immunogen: Lysed bovine corneal endothelial cells and extracellular matrix.
• Quantity: 400 μL
• Primary or Secondary: Primary
• Target Species: Bovine, Sheep
• Product Type: Antibody
• Isotype: IgG1 κ

• Applications: ELISA, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot
• Clone: A27
• Conjugate: Unconjugated
• Gene: VTN
• Gene Alias: Aa1018; AI256434; complement S-protein; epibolin; extracellular matrix protein; glycoprotein 66; serum spreading factor; serum-spreading factor; somatomedin B; Somatomedin-B; S-protein; V75; Vitronectin; vitronectin (serum spreading factor, somatomedin B, complement S-protein); Vitronectin V10 subunit; Vitronectin V65 subunit; VN; VNT; VTN
• Host Species: Mouse
• Purification Method: Protein A/G
• Regulatory Status: RUO
• Gene ID (Entrez): 101119231, 507525
• Content And Storage: 4°C, store in dark
• Form: Liquid

Safety and Handling

WARNING: Reproductive Harm - www.P65Warnings.ca.gov