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Invitrogen™ Vitronectin Monoclonal Antibody (HV23)
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Catalog No. CSI0032302
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400 μL
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CSI0032302 400 μL
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Catalog No. CSI0032302 Supplier Invitrogen™ Supplier No. CSI0032302
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Description

Mouse Monoclonal Antibody

CSI 003-23-02 is highly specific for vitronectin. There is no evidence for cross-reactivity with other connective tissue proteins (fibronectin, elastin, collagen, laminin). CSI 003-23-02 cross-reacts with vitronectin from cat, dog, goat, cow and to a lesser extent with horse. CSI 003-23-02 has been successfully used in ELISA and Western blotting techniques. By Western blot, CSI 003-23-02 detects a band of 65-75 kDa representing vitronectin. Epitope of CSI 003-23-02 is located in the somatomedin B domain, but differs from that of CSI 003-01-02. NOTE: Concentration is lot-dependent and can vary from 0.85-1.15 mg/mL.

VTN is a member of the pexin family. This protein is found in serum and tissues and promotes cell adhesion and spreading, inhibits the membrane-damaging effect of the terminal cytolytic complement pathway, and binds to several serpin serine protease inhibitors. The protein is a secreted protein and exists in either a single chain form or a clipped, two chain form held together by a disulfide bond.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Vitronectin
Applications ELISA, Western Blot
Classification Monoclonal
Clone HV23
Concentration 1.05 mg/mL
Conjugate Unconjugated
Formulation PBS with 15 mM sodium azide; pH 7.4
Gene VTN
Gene Accession No. P04004
Gene Alias Aa1018; AI256434; complement S-protein; epibolin; extracellular matrix protein; glycoprotein 66; serum spreading factor; serum-spreading factor; somatomedin B; Somatomedin-B; S-protein; V75; Vitronectin; vitronectin (serum spreading factor, somatomedin B, complement S-protein); Vitronectin V10 subunit; Vitronectin V65 subunit; VN; VNT; VTN
Gene Symbols VTN
Host Species Mouse
Immunogen Human vitronectin purified from plasma by heparin-affinity chromatography.
Purification Method Protein A/G
Quantity 400 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 100059034, 100861216, 101100765, 480621, 507525, 7448
Target Species Human, Canine, Bovine, Feline, Horse, Goat
Content And Storage 4°C, store in dark
Product Type Antibody
Form Liquid
Isotype IgG1 κ
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Safety and Handling

WARNING: Reproductive Harm - www.P65Warnings.ca.gov
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