Invitrogen™ Vitronectin Monoclonal Antibody (HV23)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ CSI0032302

Catalog No. CSI0032302

Description

CSI 003-23-02 is highly specific for vitronectin. There is no evidence for cross-reactivity with other connective tissue proteins (fibronectin, elastin, collagen, laminin). CSI 003-23-02 cross-reacts with vitronectin from cat, dog, goat, cow and to a lesser extent with horse. CSI 003-23-02 has been successfully used in ELISA and Western blotting techniques. By Western blot, CSI 003-23-02 detects a band of 65-75 kDa representing vitronectin. Epitope of CSI 003-23-02 is located in the somatomedin B domain, but differs from that of CSI 003-01-02. NOTE: Concentration is lot-dependent and can vary from 0.85-1.15 mg/mL.

VTN is a member of the pexin family. This protein is found in serum and tissues and promotes cell adhesion and spreading, inhibits the membrane-damaging effect of the terminal cytolytic complement pathway, and binds to several serpin serine protease inhibitors. The protein is a secreted protein and exists in either a single chain form or a clipped, two chain form held together by a disulfide bond.

Specifications

• Antigen: Vitronectin
• Classification: Monoclonal
• Concentration: 1.05 mg/mL
• Formulation: PBS with 15 mM sodium azide; pH 7.4
• Gene Accession No.: P04004
• Gene Symbols: VTN
• Immunogen: Human vitronectin purified from plasma by heparin-affinity chromatography.
• Quantity: 400 μL
• Primary or Secondary: Primary
• Target Species: Human, Canine, Bovine, Feline, Horse, Goat
• Product Type: Antibody
• Isotype: IgG1 κ

• Applications: ELISA, Western Blot
• Clone: HV23
• Conjugate: Unconjugated
• Gene: VTN
• Gene Alias: Aa1018; AI256434; complement S-protein; epibolin; extracellular matrix protein; glycoprotein 66; serum spreading factor; serum-spreading factor; somatomedin B; Somatomedin-B; S-protein; V75; Vitronectin; vitronectin (serum spreading factor, somatomedin B, complement S-protein); Vitronectin V10 subunit; Vitronectin V65 subunit; VN; VNT; VTN
• Host Species: Mouse
• Purification Method: Protein A/G
• Regulatory Status: RUO
• Gene ID (Entrez): 100059034, 100861216, 101100765, 480621, 507525, 7448
• Content And Storage: 4°C, store in dark
• Form: Liquid

Safety and Handling

WARNING: Reproductive Harm - www.P65Warnings.ca.gov