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QuidelOrtho VITROS™ Immunodiagnostic Products Anti-SARS-CoV-2 IgG Controls

Catalog No. OCD6199921
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For Use With (Equipment):
VITROS ECi/ECiQ/3600 Immunodiagnostic Systems and the VITROS 5600/XT 7600 Integrated Systems
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Catalog No. For Use With (Equipment)
OCD6199921 VITROS ECi/ECiQ/3600 Immunodiagnostic Systems and the VITROS 5600/XT 7600 Integrated Systems
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Rx ONLY For in vitro diagnostic and Laboratory Professional use. For emergency authorization use only
Catalog No. OCD6199921 Supplier QuidelOrtho Supplier No. 6199921
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Description

VITROS™ Anti-SARS-CoV-2 IgG test is used for the qualitative detection of IgG antibodies to SARS-CoV-2 in human serum. Intended for use as an aid in identifying individuals with an adaptive immune response to SARS-CoV-2, indicating recent or prior infection.

The VITROS™ Immunodiagnostic Products Anti-SARS-CoV-2 IgG test is performed using the VITROS™ Anti-SARS-CoV-2 IgG Reagent Pack and the VITROS™ Anti-SARS-CoV-2 IgG Calibrator on the VITROS™ ECi/ECiQ/3600 Immunodiagnostic Systems and the VITROS™ 5600/XT 7600 Integrated Systems.

An immunometric technique is used; this involves a two stage reaction.

  • In the first stage antibodies to SARS-CoV-2 present in the sample bind with SARS-CoV-2 spike protein coated on wells. Unbound sample is removed by washing.
  • In the second stage horseradish peroxidase (HRP)-labeled murine monoclonal anti-human IgG antibodies are added in the conjugate reagent. The conjugate binds specifically to the antibody portion of the antigen-antibody complex. If complexes are not present, the unbound conjugate is removed by the subsequent wash step. The bound HRP conjugate is measured by a luminescent reaction.
    • A reagent containing luminogenic substrates (a luminol derivative and a peracid salt) and an electron transfer agent is added to the wells. The HRP in the bound conjugate catalyzes the oxidation of the luminol derivative, producing light. The electron transfer agent (a substituted acetanilide) increases the level of light produced and prolongs its emission. The light signals are read by the system. The amount of HRP conjugate bound is indicative of the amount of SARS-CoV-2 IgG antibody present.

Control Contents:

  • 3 sets of VITROS™ Anti‐SARS-CoV-2 IgG Controls

Materials Required but Not Provided:

  • VITROS™ Immunodiagnostic Products Signal Reagent
  • VITROS™ Immunodiagnostic Products Universal Wash Reagent
  • VITROS™ Immunodiagnostic Products Anti-SARS-CoV-2 IgG Reagent Pack (Part No. 6199919)
  • VITROS™ Immunodiagnostic Products Anti-SARS-CoV-2 IgG Calibrator (Part No. 6199920)
  • VITROS™ Immunodiagnostic Products Reagent Pack Storage Box (optional) with desiccant

Specifications

Content And Storage 2°C to 8°C
For Use With (Equipment) VITROS ECi/ECiQ/3600 Immunodiagnostic Systems and the VITROS 5600/XT 7600 Integrated Systems
Sample Type Serum
For Use With (Application) Assesses immune response by qualitatively measuring IgG antibodies to SARS-CoV-2
Packaging 3 Sets
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