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Invitrogen™ VLK Polyclonal Antibody
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Catalog No. PIPA582916
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100 μL
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PIPA582916 100 μL
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Catalog No. PIPA582916 Supplier Invitrogen™ Supplier No. PA582916
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: STDCILEFPA RNFTLPCSAQ GWCEGMNEKR NLYNAYRFFF TYLLPHSAPP SLRPLLDSIV NATGELAWGV DETLAQLEKV LHLYRSGQ Highest antigen sequence indentity to the following orthologs: Mouse - 93%, Rat - 91%.

VLK was identified as a novel protein kinase that was induced after the differentiation of cultured embryonic stem cells into mesendoderm. It has no homologs in invertebrates, but is highly conserved in vertebrate species although it does not belong to any known protein kinase groups. VLK is initially expressed in E-cadherin-positive anterior visceral endoderm and mesendoderm, but its expression is later confined to E-cadherin-negative mesenchyme. It is enriched in the Golgi apparatus and is thought to regulate the rate of protein export from the Golgi. Targeted disruption of VLK in mice leads to a defect in lung development and neonatal lethality. It has been suggested that mutations in VLK may be associated with the allergic condition atopy.
TRUSTED_SUSTAINABILITY

Specifications

Antigen VLK
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.1 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene PKDCC
Gene Accession No. Q504Y2
Gene Alias Adtk1; AI115348; AW548124; ESTM17; Extracellular tyrosine-protein kinase PKDCC; MAd1; Pkdcc; protein kinase domain containing, cytoplasmic; protein kinase domain containing, cytoplasmic homolog; protein kinase domain-containing protein, cytoplasmic; Protein kinase-like protein SgK493; RGD1311939; SGK493; Sugen kinase 493; vertebrate lonesome kinase; Vlk; X83346
Gene Symbols PKDCC
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human PKDCC. Recombinant protein control fragment (Product #RP-95070).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 91461
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

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