Invitrogen™ VMP1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA578588

Catalog No. PIPA578588

Description

Positive Control: Unboiled HepG2 membrane extract Predicted Reactivity: Mouse (96%), Rat (98%), Zebrafish (82%), Xenopus laevis (88%), Rhesus Monkey (99%), Chimpanzee (100%), Bovine (98%) Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

VMP1 is a stress-induced protein that, when overexpressed, promotes formation of intracellular vacuoles followed by cell death. May be involved in the cytoplasmic vacuolization of acinar cells during the early stage of acute pancreatitis.VMP1 is a transmembrane protein that co-localizes with LC3, a marker of the autophagosomes. It interacts with beclin-1, a mammalian autophagy initiator, through the VMP1-Atg domain, which is essential for autophagosome formation.

Specifications

• Antigen: VMP1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: VMP1
• Gene Alias: 3110098I04Rik; 4930579A11Rik; AI787464; EPG3; HSPC292; MIR21; mir-21a; NF-E2 induceble protein-2; NF-E2-inducible protein 2; ni-2; Protein ni-2; Tango5; TDC1; Tmem49; transmembrane protein 49; Vacuole membrane protein 1; VMP1; wu:fb05d08; wu:fb92g08; zgc:77153
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 81671
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot
• Concentration: 1.64 mg/mL
• Formulation: PBS with 20% glycerol and 0.025% ProClin 300; pH 7
• Gene Accession No.: Q96GC9
• Gene Symbols: VMP1
• Immunogen: Recombinant protein encompassing a sequence within the center region of Human TMEM49. The exact sequence is proprietary.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov