Invitrogen™ VMP1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA550845

Catalog No. PA550845

Description

The antibody detects endogenous levels of total VMP1 / TMEM49 protein.

VMP1 is a stress-induced protein that, when overexpressed, promotes formation of intracellular vacuoles followed by cell death. May be involved in the cytoplasmic vacuolization of acinar cells during the early stage of acute pancreatitis.VMP1 is a transmembrane protein that co-localizes with LC3, a marker of the autophagosomes. It interacts with beclin-1, a mammalian autophagy initiator, through the VMP1-Atg domain, which is essential for autophagosome formation.

Specifications

• Antigen: VMP1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: VMP1
• Gene Alias: 3110098I04Rik; 4930579A11Rik; AI787464; EPG3; HSPC292; MIR21; mir-21a; NF-E2 induceble protein-2; NF-E2-inducible protein 2; ni-2; Protein ni-2; Tango5; TDC1; Tmem49; transmembrane protein 49; Vacuole membrane protein 1; VMP1; wu:fb05d08; wu:fb92g08; zgc:77153
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 192129, 75909, 81671
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 1.9 mg/mL
• Formulation: PBS with 40% glycerol and 0.05% sodium azide; pH 7.4
• Gene Accession No.: Q91ZQ0, Q96GC9, Q99KU0
• Gene Symbols: VMP1
• Immunogen: Synthetic peptide corresponding to residues near the C terminal of human vacuole membrane protein 1.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG