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VMP1 Rabbit anti-Human, Mouse, Rat, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA550845

Catalog No. PA550845


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Description

Description

The antibody detects endogenous levels of total VMP1 / TMEM49 protein.

VMP1 is a stress-induced protein that, when overexpressed, promotes formation of intracellular vacuoles followed by cell death. May be involved in the cytoplasmic vacuolization of acinar cells during the early stage of acute pancreatitis.VMP1 is a transmembrane protein that co-localizes with LC3, a marker of the autophagosomes. It interacts with beclin-1, a mammalian autophagy initiator, through the VMP1-Atg domain, which is essential for autophagosome formation.
Specifications

Specifications

VMP1
Polyclonal
Unconjugated
VMP1
Liquid
VMP1
Synthetic peptide corresponding to residues near the C terminal of human vacuole membrane protein 1
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human, Mouse, Rat
Immunohistochemistry (Paraffin)
1.9 mg/mL
PBS with 40% glycerol and 0.05% sodium azide; pH 7.4
Q96GC9, Q99KU0, Q91ZQ0
TDC1, TMEM49
Rabbit
IgG
100 μL
-20°C
Primary
192129, 75909, 81671
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