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Invitrogen™ VNN1 Monoclonal Antibody (C2), Invitrogen™
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Catalog No. FEMA551159
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200 μL
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FEMA551159 200 μL
FEMA551160 20 μL
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Catalog No. FEMA551159 Supplier Invitrogen™ Supplier No. MA551159
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Description

Mouse Monoclonal Antibody

Hematopoietic precursor cells migrate to the thymus, where they differentiate into mature T lymphocytes. GPI-anchored vanin-1 protein regulates the late adhesion steps of thymus homing of bone marrow precursor cells. Vanin-1 is ubiquitously expressed as a pantetheinase enzyme and catalyzes the hydrolysis of pantetheine for vitamin B5 recycling. The hydrolytic activity of vanin-1 generates the potent antioxidant cysteamine as a metabolite. As a membrane bound pantetheinase, vanin-1 provides the main source of cysteamine under normal physiological conditions. In mice, vanin-1 is expressed specifically in male Sertoli cells of the developing testis, where it aids in cell migration.
TRUSTED_SUSTAINABILITY

Specifications

Antigen VNN1
Applications Western Blot
Classification Monoclonal
Clone C2
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.05% Proclin 300; pH 7.4
Gene VNN1
Gene Accession No. O95497, Q9BDJ5
Gene Alias HDLCQ8; Pantetheinase; pantetheine hydrolase; Tiff66; V-1; vanin 1; Vanin1; vanin-1; vannin 1; vascular non-inflammatory molecule 1; VNN1
Gene Symbols VNN1
Host Species Mouse
Immunogen Recombinant Human VNN1 protein, Gln22-Gly491 (Accession #O95497).
Purification Method Protein A/G
Quantity 200 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 397246, 8876
Target Species Human, Pig
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1 κ
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