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Invitrogen™ VNN1 Polyclonal Antibody
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Catalog No. FEPA5144806
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100 μL
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FEPA5144806 100 μL
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Catalog No. FEPA5144806 Supplier Invitrogen™ Supplier No. PA5144806
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: VFPEVLLSEN QLAPGEFQVS TDGRLFSLKP TSGPVLTVTL FGRLYEKDWA SNASSGLTAQ ARIIMLIVIA PIVCSLSW Antigen sequence identity: Mouse 73%; Rat 76%.

Hematopoietic precursor cells migrate to the thymus, where they differentiate into mature T lymphocytes. GPI-anchored vanin-1 protein regulates the late adhesion steps of thymus homing of bone marrow precursor cells. Vanin-1 is ubiquitously expressed as a pantetheinase enzyme and catalyzes the hydrolysis of pantetheine for vitamin B5 recycling. The hydrolytic activity of vanin-1 generates the potent antioxidant cysteamine as a metabolite. As a membrane bound pantetheinase, vanin-1 provides the main source of cysteamine under normal physiological conditions. In mice, vanin-1 is expressed specifically in male Sertoli cells of the developing testis, where it aids in cell migration.
TRUSTED_SUSTAINABILITY

Specifications

Antigen VNN1
Applications Immunocytochemistry
Classification Polyclonal
Concentration 0.05 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene VNN1
Gene Accession No. O95497
Gene Alias HDLCQ8; Pantetheinase; pantetheine hydrolase; Tiff66; V-1; vanin 1; Vanin1; vanin-1; vannin 1; vascular non-inflammatory molecule 1; VNN1
Gene Symbols VNN1
Host Species Rabbit
Immunogen Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence. Antigen range: 436-513. Recombinant protein control fragment (Product #RP-109732).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 8876
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Format Liquid
Isotype IgG
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